Restylane and Restylane-L
These are approved for mid-to-deep injection to correct moderate to severe facial wrinkles and folds, such as nasolabial folds, and for lip augmentation.
Restylane is a well-known brand of dermal fillers. It has been trusted in the cosmetic industry for more than twenty years. Launched in the mid-1990s, as one of the first face fillers, Restylane was the first non-animal stabilized hyaluronic acid (HA) filler approved by the FDA.

Different Restylane gels have different structure, flexibility, and lifting capacity. Product selection depends on the treatment area, anatomy, and treatment goal rather than brand alone.
Private Cosmetic Dermatology Schedule Your ConsultationHyaluronic acid, the key ingredient in Restylane, is a naturally occurring substance in the skin that helps maintain hydration, volume, and elasticity.
Restylane, since its launch, has been utilized in over 65 million procedures globally. This makes it a trusted and favored option for individuals seeking to improve their looks with results that appear natural. Restylane brand offers a wide range of products designed for different treatment areas and goals, making it versatile and suitable for various aesthetic needs.
Restylane stands out due to its long history of safety and efficacy, with multiple FDA-approved formulations for various facial areas. It uses a unique gel technology that allows for a customized treatment based on the patient’s needs, ranging from more flexible, softer gels to firmer gels for more pronounced results.
The Restylane line of products is made using two special technologies called NASHA® and XpresHAn Technology™. XpresHAn Technology™ is designed to move with your facial expressions. It has a soft gel texture that is flexible and mixes well with the skin. This helps support the natural movements of your face, especially in areas that move a lot. There are more than 20 clinical studies happening around the world to test these products.
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These are approved for mid-to-deep injection to correct moderate to severe facial wrinkles and folds, such as nasolabial folds, and for lip augmentation.
This is used for cheek augmentation, correction of age-related midface contour deficiencies, adding volume to the back of the hands, and augmentation of the chin region in patients with mild-to-moderate chin retrusion.
Specifically designed for lip augmentation and the correction of perioral wrinkles (fine lines around the mouth).
An advanced formula for enhancing lip volume and smoothing upper perioral wrinkles, providing a softer and more flexible feel. These unique features make this product an ideal lip filler.
These are engineered for mid-to-deep injection into the facial tissue to smooth out laugh lines while maintaining natural expressions. Restylane Defyne is also approved for augmentation of the chin region in patients with mild-to-moderate chin retrusion.
Ideal for contouring the cheeks and restoring midface volume, providing a natural, lifted appearance. Restylane Contour is also FDA-approved for correction of temple hollowing in adults over 21.
Specifically designed for improvement of infraorbital hollowing, helping restore volume in selected patients with structural under-eye hollows.
Real patient filler results from Dermatology Circle. Individual treatment plans and outcomes vary.
Before & After
Before & AfterOne of the great benefits of Restylane fillers is that results can be seen almost immediately after treatment. The added volume from the hyaluronic acid gel smooths out wrinkles and enhances facial contours right away. However, the best results typically appear within two weeks after the procedure, as the filler settles and any initial swelling resolves.
The longevity of Restylane results depends on the specific product used and the treatment area. Generally, Restylane fillers last between 6 to 18 months. For example, Restylane-L and Restylane Lyft typically last around 6 to 12 months, while products like Restylane Defyne and Refyne can last up to 18 months when used for facial wrinkles.
Over time, the body gradually breaks down the hyaluronic acid, and treatments may need to be repeated to maintain the desired results.
Restylane fillers are FDA-approved for adults over the age of 21. There isn’t a specific “best” age to start; treatment depends on individual anatomy, volume loss, facial proportions, and aesthetic goals rather than age alone. Younger adults may seek treatment for lip enhancement or facial balance, while older adults may use Restylane to restore age-related volume loss and soften more pronounced folds.
Reveal the beauty of healthy skin with treatments tailored to you. Dr. Kazlouskaya and her team combine medical expertise with artistry to deliver natural, timeless results.